About OASIS 4 OASIS 4 was a 64-week phase 3 randomized, double-blind, placebo-controlled trial evaluating the efficacy and safety of once-daily oral semaglutide 25 mg versus placebo in 307 adults with obesity (BMI 30 kg/m 2 ) or overweight (BMI 27 kg/m 2 ) with one or more weight-related comorbidities
Expert Opin Biol Ther 10(5):801806
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The peptide is indicated for therapy in overweight or obese adults, in conjunction with a reduced calorie diet and increased physical activity, as well as in obese adolescents aged 12-17 [8]
Such modifications can result in loss of enzymatic activity, altered cellular signaling, and degradation of structural proteins, contributing to cellular dysfunction and death [36, 37]
Non-Economic Losses cover pain and suffering experienced by the affected individual